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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef5e1456586074837d779d074cc72609a9fc1d6c0922f817182ed5c856054b6' 
  AND token = 'qDo551RdN8NOIUBgfypGhJXQOZUwYuu+p5xOyRHLOQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}