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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c7d8c62c4e27be2f3630e29050d9e43024d7876fc1d40df46b0bbc3cd97df4' 
  AND token = 'oyrwH1MnqyhQlXfimfHLJ9/otxCaAmYEtMFGEGWaMj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}