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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e074b61e90388aa7b5e82718a5687f0a953a240251356b2f907022b9b4d86d87' 
  AND token = 'WVMc+naiFOi30Jm0U4i/HtaVA+x4E6qOIWFfiZ8hrVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}