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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ff59f342e25bde626480b46f28c50ce9a768a3f1dbadf6f2cad22551bd6416' 
  AND token = 'U3gBnUbHUxyEyItvniLNC8xPu4RkF52Vi0GU4RRAaQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}