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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef33f74b290845f1286690a5b359892b47fcafc6c8a0ccec3d43065d99fb0a2' 
  AND token = '4MAuC50mruVQr0utDNhPkFfTHGju5b+A3vzGu9xDsZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}