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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0779e5fbd86c2216637a8b51910380c1c7f596305bd3f5ad36b5f66644e90ed6' 
  AND token = 'SNB3MeSvqc/FgYMX7A54DFz38wJrvS3qMO7Rw+kF7TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}