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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cceca78ad69433ada49099240ae5c7386d8833483b4f46efa273a4e70b8c27f' 
  AND token = 'Pox+DHeaoOhYEr7TlG2JH8t4+qSW8/JqkkyRqycnSQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}