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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb9650f8cbfa53443a5f45032d757b3a112b2a34a783b4e58c87d9eafc547a63' 
  AND token = 'vgLMcu2Jg3BtIHgrHxKeD9Otg1CZaIcR5uNoktA1Cjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}