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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2efce48214bf1d96f10bf64c1d3e89a50c5ec56c178e2609b0cfd8aca12a95b' 
  AND token = 'S5hsGLMOaKTivrMIH0rO5AOis0xc2jNBmomX5yU7tQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}