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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1739eb6ba7b24ab599b2238ee0998814ae40d159ba47985df59dc994c7360a13' 
  AND token = 'RIt9pfaITohAhP1l1v3uWnEFmwOn46nEmGdfLPqITaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}