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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77d877efdef9be4fde2cfd3d03ad0a4172cb4b6885d4ef0b156424a5f15e7301' 
  AND token = 'Q9YUHyuDHLNc0CktvsJDyR2BAebKE7dKAtpR4Q1n+1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}