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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e6a2f0b041936aab7cfeba9100b58e38b7b24520ff4ffbdbd0de7af57a744c' 
  AND token = 'wn7ORRSBLzq+kbVT9HEfO4g2o1Ymuc1PsSMqn6ES0KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}