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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe614530a281be4c816c1b70490425922924e9f738da7b2eecdb7744a841e894' 
  AND token = '5jIaoDmLtN/VEHHY2YIBD6Iz497AIQgwfRh5Zdf3YGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}