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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aff7328677673d0034e724b777800d8d023b90cf5c5478f578c8423e5f5645e3' 
  AND token = 'aqq3QXZWhlTqMFBi5wfi7zcRFk6h5Ban6lYQPkL3+Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}