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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b346044cd1c00b25073f11ba33e427faaf7871267e94d3240a7bd9f28d5dd6' 
  AND token = 'h7Gfd1C3wQa+hxeLdJkb4r6HL8MIwptbDhlJyGPDPAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}