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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae2814c87e942d7e4b6c2067b0b96c4272aa4c72aa296727882a674d28983c5b' 
  AND token = 'as4kqyM0clh5vtFEB2rKME8I2902bHMlY6hjgdsiCA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}