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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aa7281fc7da6199d2c5b8b9993f13f2d3d805034435a98a3e63da374e88f216' 
  AND token = 'F0JlcBqUR6Lm2FEfG4JuyLJIhUCkrLta7GgCn9tfXsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}