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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110771dda5866ca75df7e1c0a6dda70bca8226c427fd2f0f852f5544923c3060' 
  AND token = 'CSSHOvo39J+DqrybjVPdtwflSbXLhy9EB5Q/PH5Qnlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}