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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b3f88852df9462dd9408691ab0fd1d9b304333700405968b44adf0d249bb04' 
  AND token = 'X49I0O1BWVOc1mkQAewSe3R7QSPva9yN9U8x/2N63v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}