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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5af6d763f6eb9e4002a1f8a27783777648b4e38f0c269ef577ed5951508d400' 
  AND token = 'Co99OlopbvVcDqNComziQVPej13laGUHSIE0SBr8Q1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}