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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e70f4053b20f99e938fc215f096a0d9489c67a8cbe0f344b5827c70b8c94cc' 
  AND token = '5JSicBpZPXKaHK8vKrr6bRjJyWNCK0XNpVBrkDxgWBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}