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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb480ea548aab3947a5baaec87699e75b43baf33ee4060dd4419bf4248cd658' 
  AND token = 'L0Qra1+0W4AoRtvxNCOWISrrQX9jsOntpwRW81BHEgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}