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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726ed9d123e8ac23bad064efece01e0cc4943d7431f3d63d896f90ac9ae53f70' 
  AND token = 'NS4IhAwd8Y+o0JKx6BHvJ93a9c8g0c9P4m7Lqgqx9c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}