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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ac03222bb54c22c27f31cdbc2cd2c7b8aa26de90d6d8d7c9ac3049e159afa0' 
  AND token = 'YHWJskepwZCO411/y6T3RNvignakAkV88dXbQtMPF4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}