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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3fe4dadf85ae5538409b412721b9b43ed286cc3fc0cc3ee082e049aa0789c32' 
  AND token = '389xYzP4Op0XizOotOATyPpree8u/HZcjGdjCDZ7HgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}