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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0481b1bfa8a2954fe955d5a4538a6c2a60d90d9b4bc1320111bc6acb06d11286' 
  AND token = 'IEwXQGAR3msk0WPZ3Hm2NBUZO2c8mYaICh79OSCt5h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}