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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a469b02b503c8ee4bd005ca2206a6dcb31dff352a2c2c6427b7ce82825365fa' 
  AND token = '+PwjgsvVtwdg668PnSNSVxx9lspUnLU5t7ziIUxD/bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}