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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4db14ebc1bd4b8425971daa6feeeaa34b9e936c3c2ff9fa96563599557b2c9' 
  AND token = 'GHE5LnCDPdcxMZnSmvkyISb03btigTV9U4r7C6wXjDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}