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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f1aa285a7a7768e4557335357dfcfbc819bbccf0891c85e1b012f4083b0c3eb' 
  AND token = 'yvk+y6OYyE72FTxQ3NEWxRU3w/yIKMG9sb93qX+OFZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}