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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7061bcdedbeab10db922358f996061f5cbd7c2c8a8e6e6036edbffba9b47bc52' 
  AND token = 'Ba4pHVc9BpYHuWE+CWWYLNyLzlee2ONAgSIfxZu5s0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}