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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65150c55bddaa605332feb49eb2d8217bcebd405b021ca458951fbe1093c573' 
  AND token = 'C9W0lt7p8v0IZLGq8vLl5j77/ZHmsRxGGkEM8liJ9YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}