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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5f0268b37be026201dbc119f09c2b3fde48428c82ce62d09701112b8b75c1cc' 
  AND token = '1oXlSYyHSki1Sax3mQSOVkC74HN5RHOV7Ocvnc2Kj2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}