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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0ff740cdc023f5d49d4cb7f203d8b12ae3ad5f2bdab04cd020552c8a970c260' 
  AND token = 'kXVNzmRB8TqgyIWfbFazxj5C/6FetM27BMS8RWh5jLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}