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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd094417e408301181016e92628edf414d5fd3b7f157da292bf5eeca71345a9e1' 
  AND token = 'hALZCe33I3an2SUl2dtENYrg2yD111/JRHOkD5JBOUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}