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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af231b5d525e7f05905eeb71d1d2f96675b2a14c47b6562a1826e8a0578aa449' 
  AND token = 'PC9TVxecuYPx69S3z1VoCMMnLXDKAneRzuwa/JQvktE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}