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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800ce710325b39534373ab3b4c3b4439dd42c2107d57e27366890bd97cde0101' 
  AND token = 'cG2m/QHlT60dp/GY1GvbupLl5FIF3E0XCE77Bl1JX5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}