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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a487cc1e45c0ebe228a4392751b061527c4256bf1cc38a0b69e2d4807a2dbb2' 
  AND token = '3ss6JAiaQqSR3NmHfZavHmWgmdEVt48Jjn068Kh8wbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}