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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c148010580c9e7cfeffe84ecb6b4eec3ed85bb2712b6b68170a5de677abca6a' 
  AND token = 'Co3V3SFJ+tRElALJwszq+0lnw/9XB14+nBXWSYa8D1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}