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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e5833c73b6e01d6b5a1b10d975161ed0cfad7c7c6df6e3682d05263ca1a707' 
  AND token = 'jKQSkr0GYl+aIwx4r0jfBPnmM1+vU8wZPCTCNGmaME4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}