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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecbfa00284b2581ad6824d8358ac3513405c42326a970b3f6ddfaa9e333f6eb8' 
  AND token = 'Zv3ajipvQ9SzdQLuZd8766wSz3e+SJAA10Rwz7Dgr7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}