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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab17e38f05169a7bfcabc540c0c0526236db501c4ad84baf0eb7aa14bbff8490' 
  AND token = '+TV+bkiDap70GoBUxZe4tyDp9vxcspBv5f7c+NYnDkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}