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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd1db0bd6d64b7485f4ba55c750c2d4124121d1b3ce221f9829b21cdcce70503' 
  AND token = 'VNtVRtwVxLXMsiRKGFKtKM1hItdeB5N8WOthW2m/qvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}