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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f893547fd0066da52068ed118f47fe76b7c447d39c0ca2e93feff6e14bab04' 
  AND token = '0N5LsSb1nnVQHiwRAKUh0YvelBY5yjjUMn5zrlRJRV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}