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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6028a2b0938350c06304f94b7c931238e4c5c2ca6bdec9591d468eb366dd194a' 
  AND token = '87VVAYuAox19UXfsc/repsrexruBIBtZthZPJLZN0I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}