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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7430f00e371e081e274fbe5b85a0e27ed14262914675ca49e2fac7b938d91c66' 
  AND token = '/6snnvvU89bVjupPMdTirCT6WOMIifkYQ/84eQ89ado=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}