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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07f1a82eeecdf027256fc3e22e85e9672b9ba62c212c05ec7b410c7d6c57ab54' 
  AND token = 'v1s5LZ45BTy9cwh2X0PfWkSQ/3mwGw76HV2mCXDrP2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}