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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e06971fc6d7fcac340a0102eeb2eaebb121056d7fb8a06cb774bccb30e5c60' 
  AND token = 'DARlrUB/MbrLy+e7fzU8xVYDNDsgNmB+nQhh+d0/YEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}