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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1981540a55e426a21b31a28c64d684496ff60f27511c95a51e73cdecbcf0e081' 
  AND token = '6TPBJ4738TYtX7nIY6fRlg0lN6qPHl8BDDFtqwZADI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}