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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4303edc755c51840441c22478f6fe93d01f888f7286d11d8b57f849a92d9fa42' 
  AND token = 'nyEjCNY7dSS8Au1BsndWHt9o1v5gmdo6/ou8iWoA9oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}