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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f3d2fb03f6f84a70514a2756f07f4ba71920ac23a8c0d3c6a5d7881ece50341' 
  AND token = 'Liwj97q3toto0rwqSYPuJ7+akN1IUtncXKiHWhMBAwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}